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br There was evidence of synergistic
2020-07-06
There was evidence of synergistic effect-measure modification, on the additive and multiplicative scales, by BMI for six air toxics, in-cluding 2,4-toluene diisocynate, benzidene, Herboxidiene dichloride, ethy-lene oxide, hydrazine, and propylene dichloride (Table 5). In the stra-tified analyses,
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br In terms of the mechanisms underlying ACSL
2020-03-24
In terms of the mechanisms underlying ACSL4-regulated cell re-sistance to chemotherapeutic drugs, the evidence reported here sug-gests that ACSL4-dependent resistance could involve the activation of the mTOR pathway. Our current results show that mTOR inhibition and ACSL4 inhibition work in combin
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br Postoperative outcomes br Adverse events during the first
2020-03-24
Postoperative outcomes Adverse events during the first 30 days postoperatively were recorded and graded according to Clavien-Dindo [25]. Grade three or more was regarded as severe, defined as AEs that EPZ-6438 resulted in surgical, endoscopic or radiological intervention (grade 3), IC/ICU manag
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br vesicle in the control group
2020-03-24
vesicle in the control group. In contrast, different RAP formu-lations used in single or in combination induced a large number of green spots of autophagic vesicles. Only a small amount of autophagic vesicles was induced by free PTX alone. This may be due to the fact that the free drug is highly l
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br on a micrometer scale Vernier caliper An
2020-03-24
on a micrometer scale (Vernier caliper). An image of the tumor section was acquired and stored in JPEG format. The camera lens was posi-tioned vertical to the tumor section during image acquisition (Fig. 1b). Then, the surgical specimens were preserved in formalin solution. Pa-thological sections
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br nCounter elements gene expression analysis Gene
2020-03-24
nCounter elements gene P 22077 analysis. Gene expression levels in training and testing sets were quantified via the nCounter Elements approach, according to manufacturer’s instructions (NanoString Technologies, Seattle, West Coast). Briefly, probes were designed to target sequences of interest a
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br P P Sarmah D K Dutta Chemoselective reduction of
2020-03-24
[28] P.P. Sarmah, D.K. Dutta, Chemoselective reduction of a nitro group through transfer hydrogenation cat frameborder="0" allow="accelerometer; autoplay; encrypted-media; gyroscope; picture-in-picture" allowfullscreen>alysed by Ru 0-nanoparticles stabilized on modified Montmorillonite clay, Green
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br Participant information was collected on date of
2019-11-12
Participant information was collected on date of birth, gender, cancer type, time since diagnosis, treatment received, time since completion of treatment, response to treatment and ethnic group to assess baseline characteristics between arms. The structure of the questions used to obtain the
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br B F metastatic model The mice were sacrificed
2019-10-30
B16-F10 metastatic model. The mice were sacrificed on day 14 there-after, and the lungs were checked for tumor nodules (Figure 4E). An average of 257 and 242 nodules were found in the PBS and DTT groups, respectively, whereas an average of 92 and 79 nodules were found in the DPDL1E group and mAb g
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br The fact that albumin masking was largely eliminated from
2019-10-29
The fact that albumin ‘masking’ was largely eliminated from the in vivo liposomal corona (Fig. 1D) prompted us to investigate whether intravenously injected liposomes can form coronas with Dalbavancin pro-teins that cannot be directly detected by proteomic analysis of plasma control samples. Plas
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br Among patients with cm of re sidual
2019-10-21
Among patients with 1 cm of re-sidual disease confined to a single anatomic site (n¼34), the most com-mon locations of residual disease tu-mor nodule(s) were the SC 560 (41.2%), bowel mesentery (20.6%), and the pelvis (17.6%). Other loca-tions for residual disease included bowel serosa (11.8%), p