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br DLS studies were conducted to
2020-08-07
DLS studies were conducted to obtain the mean particle size and surface charge of the Coleus aromaticus extract-mediated CuO NPs. Fig. 4A shows the size distribution of the CuO NPs; a mean particle size of 33 nm was observed, and the size distribution was in agreement with the TEM results. The sur
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br After h from the start of the
2020-08-07
After 24 h from the start of the release test, the cumulative PTX release rate of PTX-micelles at pH 7.4 was 30.8%. This result indicates that PTX was properly encapsulated in micelles. At pH 5.0, the cumulative PTX release rate of PTX-micelles was significantly higher than that at pH 7.4. Therefo
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Eight week old male Balb c mice obtained from Southern
2020-08-07
Eight-week-old male Balb/c mice obtained from Southern Medical University. 106 Phosphatase Inhibitor Cocktail II were injected below the breast into the abdomen of the mice for subcutaneous tumor xenografts. When the tissues grew to 90–120 mm3 (8–10 days after injecting the cells), the mice were gr
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br These authors contributed equally Lead Contact Correspond
2020-08-07
7These authors contributed equally 8Lead Contact *Correspondence: [email protected] (V.I.S.), [email protected] (M.O.B.) SUMMARY For tumors to progress efficiently, cancer SPDP must overcome barriers of oxidative stress. Although die-tary antioxidant supplementation or activation of endo
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br Table Demographic Clinical and Pathologic Characteris tic
2020-08-06
Table 2 Demographic, Clinical, and Pathologic Characteris-tics of Studied Population Breast Cancer Control P Menstrual History Family History Tumor Type TNM Stage Tumor Size Metastasis ER/PR Data are presented as n (%) unless otherwise indicated. Abbreviations: ER ¼
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br Conflict of interest statement br Dr
2020-08-06
Conflict of interest statement Dr. Matei reports personal fees from Astra Zeneca, Genentech/Roche, Tesaro, Astex, Clovis, and the European commission that Gilteritinib are outside the submitted work. All other authors report no conflicts of interest. Author contributions Conceptualization
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br In conclusion biomarkers of inflammation IL and CRP and
2020-08-06
In conclusion, biomarkers of Selamectin (IL-6 and CRP) and me-tabolism (resistin) were significantly associated with increased risk of cancer mortality independent of obesity, suggesting that both pathways may play a synergistic role in creating a favorable microenvironment for tumorigenesis and
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br according to the manufacturer s protocol The
2020-08-04
according to the manufacturer’s protocol. The culture medium was centrifuged at 3000×g for 15 min to remove cells and debris. Then, the supernatants were transferred to new tubes, and the reagents were added. After overnight incubation, the samples were centrifuged at 10,000 × g for 30 min. The
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br enhance sensitivity of chemotherapeutic agents br Conclus
2020-08-04
enhance sensitivity of chemotherapeutic agents. 5. Conclusion Co-delivery of DOX and SC by NLC-RGD is an appropriate approach to overcome MDR problems of DOX. Results of this study suggested that loading of SC and DOX into NLC-RGD prepare them more effective in accumulation into cancerous ce
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br The results of MTT cell viability assay
2020-08-03
The results of MTT cell viability assay on HER 2 positive breast cancer cell line (SK-BR3) are reported in the bar charts of Fig. 5. The results showed that cell viability was dependent on CCM concentration and in-cubation time which has decreased by increasing the drug dose and ex-posure time. Ac
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A br B br solubility
2020-08-03
A B solubility and potential enhanced antitumor effects. Therefore, the anti-tumor efficacy of CNC was studied systematically in the following sections. 3.2. In vitro cytotoxicity of CNC The in vitro cytotoxicity assessment was conducted by MTT assay in SGC-7901 AZD8931 at gradient c
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br ANGPTL expression was associated with the
2020-07-29
3.2. ANGPTL6 expression was associated with the microvessel density of AFPGC patients To investigate the importance of ANGPTL6 in gastric cancer, com-pared to patients with a low expression of ANGPTL6 (Fig. 2A), patients with high levels of ANGPTL6 had a poorer prognosis. In addition, we found
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br Keywords brush cytology ERCP microRNA pancreatobiliary br
2020-07-28
Keywords: brush, cytology, ERCP, microRNA, pancreatobiliary ACCEPTED MANUSCRIPT INTRODUCTION Projected cancer death of bile duct and pancreatic cancers, surpassing breast, prostate, and colorectal cancers, are expected to become second and third leading causes of cancer-related death by 2
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Clearly the methodology developed here and demonstrated for
2020-07-27
Clearly the methodology developed here and demonstrated for the detection of HER2 mRNA biomarker, is a universal platform applicable for the detection of any genetic material. It is noteworthy that the dUHBI monomer preserves the natural H-bonding pattern of dU and can be used as a monomer in a s
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br It has been well established that HK is
2020-07-06
It has been well-established that HK2 is associated with the cellular inhibition of apoptosis. As shown in Fig. 5D and E, although the over-expression of AKT2 increased the level of the anti-apoptosis-related protein (B-cell lymphoma-2 and B-cell lymphoma-XL, Bcl-2 and Bcl-XL) expression, knocking